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WN@tL: Fighting Antibiotic Resistance with Broken Scissors
October 23, 2019 @ 7:00 pm - 8:30 pmFree
Speaker: Jason Peters
Speaker Bio: Dr. Jason M. Peters is an assistant professor at the University of Wisconsin-Madison, where he uses CRISPR tools to investigate the genetics of pathogenic bacteria that are associated with antibiotic resistance with the goal of identifying new weaknesses in these pathogens that can be therapeutically exploited. Jason received his Ph.D. in Genetics from the University of Wisconsin-Madison, where he studied the fundamental mechanisms of bacterial transcription termination in the laboratory of Robert Landick. As a postdoctoral fellow at the University of California, San Francisco in the laboratory of Carol Gross, Jason developed CRISPR-based tools that enabled systematic analysis of essential gene function and dissection of genetic redundancy in the envelope of the model Gram-positive bacterium, Bacillus subtilis.
Desription: Antibiotic-resistant bacterial pathogens are directly responsible for the deaths of tens of thousands of people in the United States each year, and the problem is growing worse over time because we have not been able to find new weaknesses in pathogens that we can target with antibiotics. I am developing CRISPR-based strategies to identify such weaknesses by probing genes that are central to bacterial life on a massive scale. The knowledge I gain from my studies will be directly relevant for controlling bacterial pathogens and determining how antibiotics work.